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The Indianapolis Colts (3-2), who are fresh off a big divisional win against the Tennessee Titans, will face another familiar AFC South foe, the Jacksonville Jaguars (3-2).
As a result of the tie-breaker from winning the opener against the Colts, Jacksonville technically leads the division, which makes this game all the more important for Indianapolis to avoid being swept for the season—as it relates to retaking the division.