The Indianapolis Colts had no business risking a loss to the Arizona Cardinals. Arizona was without its starting quarterback, Kyler Murray, and lost its top running back early in the season. Indy was facing long-term backup Jacoby Brissett and should have been able to limit the Cards to 20 points, at most.
But just as quarterback Daniel Jones gives, defensive coordinator Lou Anarumo gives away. Indy is capable of making a playoff run. The AFC South is not that good overall. Indianapolis is probably going to win both games against the Tennessee Titans, and maybe against the Houtson Texans.