The Indianapolis Colts don't necessarily have a must-win game against the Jacksonville Jaguars in Week 14, but it's close. If Indy were to lose, its playoff hopes are not dashed. Far from it, as the team would still be in a position to win the AFC South with some victories to finish the season.
As far as key players missing the game, Colts fans already knew that defensive lineman DeForest Buckner would miss the contest with a neck injury. He is on injured reserve, and there is no real timeline for his return. He and the team hope he can come back during the regular season.