An NFL team simply cannot be scared. If a team lets one defender take half the field away, the offense is limited, and defeat might have already been admitted. The Indianapolis Colts refused to do this against the Denver Broncos in Week 2, though.
Instead, quarterback Daniel Jones and head coach Shane Steichen ran the offense they wanted to run, and it didn't matter where cornerback Patrick Surtain II, the reigning Defensive Player of the Year, was lined up for the Denver Broncos. If Jones was planning on tossing a ball somewhere, he did so.
Against the Colts, Surtain allowed seven completions when he had primary coverage.