return home to Lucas Oil Stadium for a matchup with the Cleveland Browns (-2). For both teams being in the AFC, these two do not meet very often. They have only played each other four times since 2012 with the last meeting being a 32-23 win for the Browns in 2020. DraftKings Sportsbook is giving the early edge to the Browns in this one.
The Colts are coming off a bit of a disaster against the Jacksonville Jaguars (+1)
. Life without their quarterback set in as Gardner Minshew struggled mightily after a promising opening drive.