Andrew Luck misses first practice of 2016

(Photo: Matt_Kryger/Indy_Star)Zach Kerr, Phillip Dorsett, Andrew Luck, D'Qwell Jackson and coach Chuck Pagano of the Indianapolis Colts discuss the Week 3 matchup against the San Diego Chargers.Clark Wade/IndyStar

Here we go again?

The Colts sure hope not.

Star quarterback Andrew Luck missed his first practice of the season Wednesday, resting that sore right shoulder of his. He said he anticipates practicing on Thursday but will defer to the training staff and coaches to make the final decision.

The natural concern for the Colts, after watching Luck miss nine games in 2015: Is there a reason for alarm?

“I don’t think so,” Luck said. “But I don’t raise the alarms. That’s you guys.”

Of the seven…