Tottenham defender Toby Alderweireld is expected to keep his place, having made his first appearance in two months against Manchester United on Sunday.
Mousa Dembele was substituted during that game after being kicked on the foot, making him a fitness doubt.
Hull's side is set to include a number of former Spurs players, including captain Michael Dawson and midfielders Jake Livermore and Tom Huddlestone.
Will Keane and Abel Hernandez remain long-term absentees.
MOTD COMMENTATOR'S NOTES
Steve Bower: "After just a second defeat of the season at Old Trafford, this might have been Spurs' choice of fixture to get back to winning ways.