Grant McCann will give opportunities to players who featured for the U23s on Monday when Hull City entertain Fleetwood.
A strong team lined up for the U23s fixture against Charlton Athletic, with the likes of George Long, Dan Batty and James Scott all starting.
The Tigers are in FA Cup first-round action against fellow League One side Fleetwood this afternoon and McCann has said he will make changes.
“Most of the team that played on Monday will have an opportunity,” said McCann.
“Not all of them will play but some of those players will get an opportunity to play in this game.