Throughout NFL history various quarterbacks have had the number of specific opponents. Recent examples that come to mind are Tom Brady vs. the Buffalo Bills, Aaron Rodgers vs. the Chicago Bears, and Ben Roethlisberger vs. the Cleveland Browns, but on a much smaller scale, it's important to acknowledge that for whatever reason, whenever Sam Darnold plays against the Houston Texans, it's like he's putting together an audition tape for Canton.
In his career, Darnold is 2-1 in three starts versus Houston, and interestingly, all three of those games have came with a different team. But regardless of if he was in New York, Carolina or Minnesota, Darnold seems to have the number of the Houston Texans.