At TDECU Stadium, the Cougars and Bearcats will square off on Saturday at 6 p.m., as Houston looks to defeat Sam Houston for the fifth time in a row.
The Cougars aim to rebound as they get ready for their first meeting against Sam Houston since 2005 after dropping the Big 12 home opener against TCU last week.
Both teams will clash for the seventh time overall, with the Cougars holding a 4-2 advantage in the all-time series against the Bearcats.
The last time Houston and Sam Houston faced off, Houston prevailed 31-10.
Unfulfilling Big 12 Debut
After coming off a heartbreaking 43-41 overtime loss to Rice in the Bayou Bucket, the Cougars looked to turn the tables going into their first Big 12 game, but things didn’t go as planned.