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Roberto Osuna gives up two homers but the Astros hold on to win 6-5

Gerrit Cole gave up a two-run home run to the third batter that he faced, but he would not allow another run to cross the plate. He finished with 12 strikeouts and only one walk in his six innings of work for the Astros.

Down 2-1 going into the 3rd inning, the Astros would put up five runs. Yuli Gurriel, who had three hits on the day, would tie things up with an RBI single and Robinson Chirinos would double, bringing in Gurriel to give Houston the lead.

In his MLB debut, Jack Mayfield, who doubled in his first ever at-bat, drove in the third run of the inning with a sac fly.