The preseason has concluded and the next order of business for GM Brad Holmes and head coach Dan Campbell is trimming the roster down to an initial 53 players by 4 p.m. Tuesday and then beginning to create their 16-man practice squad on Wednesday.
After that, they'll get to work on the Green Bay Packers and the rest of the early slate of opponents on the regular season schedule.
Following is a look at the Lions' first four games of the 2025 NFL season:
Week 1 at Green Bay Packers, Sept. 7, 4:25 p.m.
A Week 1 NFC North showdown featuring two division rivals and two playoff teams from last year.