As much as the 49ers QB has beaten the Packers with his legs in the past, it’ll be up to Julius Peppers, Mike Neal, Nick Perry, et al to set the edges and keep him contained. This game won’t be about sacking Kaepernick, it’ll be about not letting him run.

2. Mike Daniels vs. Alex Boone – There’s no telling how often the Packers’ best interior pass rusher will line up across from the 49ers’ veteran left guard, but when it happens, it’ll be worth watching.