Phil Jagielka has pulled out of the England squad to face Malta and Slovenia with a thigh strain.
The Football Association announced the Everton defender has returned to his club for treatment but is expected to be fit for the Toffees' Premier League trip to Manchester City next Saturday.
Interim boss Gareth Southgate has no immediate plans to call up a replacement ahead of Saturday's World Cup qualifier with Malta at Wembley.
Jagielka did not take part in the full England training session on Tuesday following Everton's 1-1 draw with Crystal Palace on Friday but his absence was planned.