There are some songs across genres that just really pack a punch. Django Rheinhardt’s version of Night and Day (the electric version as opposed to the various acoustic covers), Crazy by either Patsy Cline or Willie Nelson who wrote it, The Weight by The Band, maybe Choices by George Jones as he understood that decades of substance abuse meant he was going to die soon.
There are others but you get the idea.
There are a lot of them really and a whole lot of them are in soul music. Think Rainy Night in Georgia or Dark End of the Street.