The Tigers hitters continue to be unsure at the plate as Lucas Giolito has been keeping them off balance, nibbling the corners and getting the benefit of a few calls.
Tucker Barnhart and Robbie Grossman both struck out before Austin Meadows drew a two-out walk.
Any hopes of some offense, however, were wiped out when Javier Baez struck out for the second time to end the third inning.
White Sox go down in order but lead Tigers, 3-0
The Tigers had their first easy defensive inning of the season as Eduardo Rodriguez was able to get the White Sox out in order in the third, throwing 15 pitches for a total of 73.