21-20 victory over the defending Super Bowl champion Kansas City Chiefs (-2.5), handing quarterback Patrick Mahomes his first opening game loss of his career. It was a gritty win for the Lions, but they showed their ability to fight through adversity and that they are capable of beating any team in the NFL.
On Sunday, the NFL has 14 games scheduled and the local Detroit audience will have a chance to watch all three of their division rivals. The 1 p.m. ET timeslot will have the Tampa Bay Buccaneers (+5)
at Minnesota Vikings (-5) on CBS, while FOX will televise the San Francisco 49ers (-2) at Pittsburgh Steelers (+2).