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Week 12 NFL Picks: Potential playoff preview when Packers visit 49ers

Game of the week

Green Bay at San Francisco

The 49ers are a three-point home favorite in what could be a preview of the NFC title game. The Packers are coming off their bye week. We still think San Francisco is the conference favorite, but it lost to Seattle and struggled against Arizona in its last two games.

Packers 27, 49ers 24

Lock of the week

Jacksonville at Tennessee

The highlight of the Jaguars’ season will end up being their come-from-behind win at the Broncos.