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Week 10 NFL Picks: Undefeated San Francisco hosts division rival Seattle in Monday night showdown

Seattle at San Francisco

A Monday night clash between the 8-0 49ers (a six-point favorite) and 6-2 Seahawks, the first of two meetings. If San Francisco wins, it will have a three-game NFC West lead with seven games remaining and is in driver’s seat for home-field advantage. If Seattle wins, it still has a chance to win the division. Seahawks 24, 49ers 21

Lock of the week

Atlanta at New Orleans

Both teams are coming off their bye weeks and headed in opposite directions. The 1-7 Falcons lead the NFL in passing yards (316.