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Denver Broncos sign RB Latavius Murray; Javonte Williams, Randy Gregory to injured reserve

The Denver Broncos signed veteran running back Latavius Murray off the New Orleans Saints' practice squad on Tuesday and placed starting running back Javonte Williams and starting outside linebacker Randy Gregory on injured reserve.

It's unlikely that Murray will play this Thursday night against the Indianapolis Colts, a source told ESPN, confirming multiple reports.

Williams, the Broncos' leader in carries and rushing yards, will miss the rest of the season because of a right knee injury suffered on the Broncos' first play of the second half in Sunday's 32-23 loss to the Las Vegas Raiders, coach Nathaniel Hackett announced Monday.