The Denver Broncos game-day inactives against the Carolina Panthers were: Zach Wilson, PJ Locke, Kris Abrams-Draine, Alex Palczewski, Greg Dulcich, Dondrea Tillman, and Eyioma Uwazurike. Both Locke and AP were inactive because of injury. The rest were healthy scratches.
Offense
| Player | Pos | Num | Pct |
| Ben Powers | G | 73 | 100% |
| Alex Forsyth | C | 73 | 100% |
| Bo Nix | QB | 73 | 100% |
| Garett Bolles | T | 72 | 99% |
| Quinn Meinerz | G | 72 | 99% |
| Mike McGlinchey | T | 72 | 99% |
| Courtland Sutton | WR | 61 | 84% |
| Lil'Jordan Humphrey | WR | 44 | 60% |
| Javonte Williams | RB | 42 | 58% |
| Adam Trautman | TE | 41 | 56% |
| Nate Adkins | TE | 35 | 48% |
| Lucas Krull | TE | 27 | 37% |
| Troy Franklin | WR | 27 | 37% |
| Devaughn Vele | WR | 25 | 34% |
| Jaleel McLaughlin | RB | 23 | 32% |
| Marvin Mims | WR | 21 | 29% |
| Michael Burton | FB | 11 | 15% |
| Audric Estime | RB | 5 | 7% |
| Matt Peart | T | 4 | 5% |
| Calvin Throckmorton | G | 1 | 1% |
| Frank Crum | T | 1 | 1% |
Our QB and our entire OL played every snap with the exception of one kneel-down snap at the end of the game where Matt Peart, Frank Crum and Calvin Throckmorton got to play on offense.