The Denver Broncos are travelling to Indianapolis for their first road matchup of the 2025-26 season, specifically against the Colts. The game is on Sunday, September 14th, at Lucas Oil Stadium. It is their second consecutive game against an AFC South team, as they defeated the Tennessee Titans at home last weekend by a 20-12 score, not allowing a single touchdown.
Broncos quarterback Bo Nix saw action for the first time as an NFL player last year during the preseason against this Colts team at Lucas Oil and alongside the rest of the offense, will look to have a bounce-back game to start the season 2-0.