Manchester United interim manager Ralf Rangnick is likely to be without Raphael Varane, Paul Pogba and Edinson Cavani for his first match in charge.
Left-back Luke Shaw remains doubtful as he continues to recover from a head injury.
Crystal Palace defender Joel Ward is suspended as a result of receiving his fifth booking of the season in midweek.
Joachim Andersen and James McArthur are unlikely to return from thigh injuries, while Nathan Ferguson remains out.
LAWRO'S PREDICTION
Ralf Rangnick takes charge of Manchester United for the first time on Sunday and I'm definitely expecting a reaction from their players.