Crystal Palace captain Luka Milivojevic begins a three-match suspension following his sending off at Wolves.
Gary Cahill and James Tomkins continue to be monitored after injury but Wayne Hennessey and Connor Wickham are out.
Leeds are assessing the fitness of winger Raphinha, who missed Monday's loss to Leicester with an ankle issue.
Rodrigo has been ruled out because of a positive test for coronavirus, while Kalvin Phillips and Diego Llorente remain on the sidelines through injury.
LAWRO'S PREDICTION
Crystal Palace have had the fewest shots of any team in the Premier League, with 57 in seven games, while only Liverpool have had more than Leeds.