Nathan MacKinnon and Cale Makar Suffer Injuries as Avalanche Fall to Senators

The Colorado Avalanche could be facing a significant setback after Nathan MacKinnon and Cale Makar both exited Thursday night's 4-3 overtime loss to the Ottawa Senators with lower-body injuries, casting an unsettling shadow over the team's latest stop at Canadian Tire Centre.

Losing either player would be a considerable blow. Losing both in the same game is an entirely different concern for a Colorado team chasing a Central Division title.

MacKinnon was the first to leave, with his final shift coming at the 8:15 mark of the second period. The star center appeared to grab his right side after attempting a reverse hit on Ottawa defenseman Artem Zub. He remained on the bench briefly before…