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49ers vs Browns: 6 factors that could lead to an upset

Pretty much everyone covering the NFL has chalked up a victory for the San Francisco 49ers (-9.5)

over the Cleveland Browns (+9.5). The 49ers-Browns point spread has climbed to 10 points in most places putting Cleveland’s odds of winning very low.

Those odds are not zero, however.

The Browns do have a chance to win today’s game in Cleveland even if that chance is slim. Not having QB Deshaun Watson, RB Nick Chubb, OL Joel Bitonio & Jack Conklin and WR Cedric Tillman, along with TE David Njoku (who is expected to play) and OL Ethan Pocic being questionable, will greatly impact the offense.