ESPN just named Clemson as having the toughest Power 4 non-conference schedule in 2025, with a brutal slate including a Week 1 showdown with LSU and a season-ending rivalry clash at South Carolina.
The gauntlet has been laid! As college football teams gear up for fall camp, ESPN has released its "schedule superlatives" for the 2025 season, and the verdict is clear: the Clemson Tigers have been tabbed with the toughest non-conference schedule in the entire Power 4.