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Opening odds: Clemson begins game week vs. LSU as 4-point favorite

Related Topics: LSU Tigers football, Clemson

No. 4 Clemson heads into the first game week of 2025 favored at home against No. 9 LSU.

In a betting market that opened several months ago, Clemson started as a 2.5-point favorite. The ACC Tigers have continued to take enough money to increase the spread. Most U.S. sportsbooks have Clemson at -4.

The spread in one of the most intriguing games of Week 1 has reached as high as 4.5 at FanDuel, but the sportsbook had it at 3.5 as of Sunday afternoon. DraftKings, which has Clemson -4, has actually seen LSU receive most of the money, with the SEC Tigers coming in a 56% of the handle, which is the amount of money wagered in a particular betting market.