The Clemson Insider · Nov 29, 2025
College Gameday Analysts Give Their Picks for Clemson-Carolina
The College GameDay selections are in for college football Rivalry Week.
ESPN’s College GameDay crew has made their picks for today’s matchup between Clemson (6-5) and South Carolina (4-7) at Williams-Brice Stadium in Columbia.
South Carolina comes in as a 2.5-point favorite on the spread for the game (noon, SEC Network).
Clemson is 7-2 against South Carolina in the last 10 years, with the two schools not meeting in 2020 due to a cancellation because of COVID. Clemson has won eight of the last 10 meetings in the rivalry overall, though South Carolina has won two of the last three meetings, both at Clemson. The Tigers lead 73-44-4 in the all-time series.