Clemson jumped out to an early 7-0 lead on a five yard touchdown pass from Trevor Lawrence to E.J. Williams with 11:56 to play in the first quarter. The drive covered 16 yards in three plays and 0:36.
Freshman Malcom Greene intercepted Kenny Pickett to give the Tigers the ball at the Pitt 16. Lawrence completed a one-yard pass to Amari Rodgers then Travis Etienne carried the ball 10 yards to the Pitt five that set up the five yard touchdown pass to Williams.