No. 4 Clemson opens the 2025 season with a huge test against No. 9 LSU. Neither team will be knocked out of the College Football Playoff hunt with a loss, but neither team has impressed in their opener in quite a while, so there’s a lot on the line tonight with the ball kicks off at 7:52.
This is also one of three marquee, top-10 showdowns in Week 1. There has never been more to start the season. So the hype machine is strong with this one. Bettors have had their eyes on this matchup all summer, so here’s a wagering primer to get you ready for a battle between two Tigers inside one Death Valley.