Deshaun Watson threw a 34-yard touchdown pass to Jordan Leggett with 3:14 to play in the game as No. 5 Clemson rallied to beat Lamar Jackson and third-ranked Louisville, 42-36, on October 1, 2016.
Watson threw five touchdown passes and had 397 total yards, including 306 passing yards, while Jackson had 457 total yards and totaled three touchdowns in a battle of top 5 teams at Memorial Stadium. Jackson went on to beat out Watson for the Heisman Trophy that season, but Watson and the Tigers earned the bigger prize … the 2016 National Championship.
After Clemson fell behind 36-28 with 7:52 to play in the game, following Jackson’s 11-yard scoring run, Watson engineered two quick scoring drives to put Clemson back in front.