The Angels are, apparently, committed to trying a six-man rotation. This is interesting, but as FanGraphs pointed out, also problematic because of the strain it puts on the roster. I would add that pitchers tend to get hurt, after all, and most teams have a hard time filling a five man rotation. So a six man rotation is going to be even harder even without the roster crunch.
One of the things that gets lost from time to time is that we still have no idea how to prevent pitcher injuries. There are numerous write ups and studies with no evidence that anything makes a huge difference except that there is a correlation between extreme fatigue and injury.