Will the Fire choose their "standard" formation - will they choose the formation which stymied New York City FC - or will they try something different?
From a confidence standpoint, last week's 1-1 draw against a determined Orlando City side that was a man up for 60+ minutes demonstrated that Fire coach Veljko Paunovic and his players can adapt on the fly no matter what the game throws at them.
This week will present a new challenge in the form of Chicago's biggest rival and the 2015 MLS Cup runners-up.
Lining up the Columbus Crew
From a tactical standpoint, there has been no reason the Crew are 0-2-0 at this point in the season.