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Chicago Cubs Lineup (5/16/25): PCA Leads Off, Ballesteros DH, Horton Making First Start

The Cubs open their first series against the White Sox on Friday afternoon at Wrigley, and they’ll do so with their top pitching prospect making his first start in his home debut. Should be a fun day at the ballpark with Cade Horton showing what he can do. After opting for an opener to bypass the top of the Mets’ vaunted lineup in his MLB debut, Craig Counsell is getting Horton back to a standard routine against a far inferior offense.

Horton looked good outside of one mistake, striking out five and issuing no walks over four innings of work.