Chelsea's Sam McClelland and Liverpool's Conor Bradley have been handed first senior Northern Ireland call-ups for the friendlies against Malta and Ukraine.
Bradley, 17, has also featured for the U17s and played in Liverpool's FA Youth Cup Final defeat by Aston Villa earlier this week.
Steven Davis and Jonny Evans are among the experienced players rested.
Corry Evans, Conor McLaughlin, Jamal Lewis, Michael Smith, Michael McGovern and Trevor Carson will also not be involved in the behind-closed-doors match against Malta in Austria, which has been brought forward from Monday to Sunday, and next Thursday's game in Ukraine.