Leeds United will wait until matchday to assess whether Patrick Bamford and Liam Cooper are fit to be involved.
Chelsea's N'Golo Kante faces a month on the sidelines following a hamstring strain against Tottenham.
Head coach Thomas Tuchel confirmed that Armando Broja and Mateo Kovacic are out.
CHRIS SUTTON'S PREDICTION
Leeds boss Jesse Marsch will have been deeply disappointed to see his side pegged back by Southampton after going two goals up, and I think he might have to deal with another setback here.
There are still a few question marks over what is going on with Chelsea up front, and they keep getting linked with new players too, but they were excellent against Spurs last week.