Crystal Palace will be without on-loan striker Michy Batshuayi, who is ineligible to face his parent club.
They are boosted by the return of James McCarthy and Tyrick Mitchell, but Connor Wickham has a minor injury and joins a lengthy list of absentees.
Chelsea head coach Thomas Tuchel gave his side a clean bill of health in his pre-match press conference.
However, central defender Thiago Silva is suspended as a result of his sending off at West Brom last weekend.
LAWRO'S PREDICTION
Chelsea were on the wrong end of a stunning 5-2 scoreline against West Brom last weekend, but they bounced back well against Porto in midweek.