Chelsea will hope to welcome back Andreas Christensen and Ross Barkley as the pair step up their recovery from illness.
Midfielder N'Golo Kante could also return after he missed the defeat at Everton with a minor injury.
Wolves head coach Bruno Lage will be absent after testing positive for Covid-19.
Winger Daniel Podence has returned to training after a month out with a foot injury and is likely to be involved.
Nelson Semedo will join fellow defender Max Kilman on the sidelines for the remainder of the campaign.
LAWRO'S PREDICTION
I thought Chelsea were bullied a bit in their defeat by Everton last weekend, which was strange to see.