Christian Pulisic could feature after the hamstring injury sustained in Chelsea's warm-up against Burnley last weekend was found to be minor.
Injured Sheffield United pair John Fleck and Lys Mousset have stepped up their rehabilitation but won't feature.
The Blades will also be without loanee Ethan Ampadu, who is ineligible to face his parent club.
LAWRO'S PREDICTION
Sheffield United just can't score goals. Since beating Chelsea 3-0 in July, they have only managed four in 10 league games - and two of those were penalties.
They have picked up only one point in that spell, when their performances haven't actually been that bad - so it is obvious where their problems lie.