Roma are gearing up for what is surely an impossible task tonight by trying to overhaul a four-goal deficit in their semi-final second leg against Manchester United in the Europa League.
But incredible comebacks have happened before in football and Roma have even played their part in one of the most incredible of them all.
Manchester United beware - commanding leads have fallen in Europe before and here, Sportsmail looks back at some of the most epic comebacks on the continent.
ROMA 3-0 BARCELONA, 2018
After being defeated 4-1 by Barcelona in the first leg of their Champions League quarter-final in 2018, the writing seemed to be written on the wall for Roma.