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Top-Ranked Clemson Hands 49ers Non-Conference Loss

Clemson, S.C. -- The Charlotte 49ers (2-2) dropped a 52-10 decision at #1/#1 Clemson (4-0), Saturday night at Memorial Stadium. It is the first time the 49ers have faced the nation's top-ranked team.

The defending national champs ran out to a 38-3 halftime lead thanks in part to two Trevor Lawrence touchdown passes and a 66-yard interception return.

Lawrence hit Tee Higgins for a 58-yard TD on the Tigers second play from scrimmage and K'Von Wallace added his 66-yard pick six to put the Tigers ahead 14-0, 4:36 into the game.

"They came out and got after us," said 49ers head coach Will Healy.