The collective groan you heard on Sunday was NFL fantasy players. Two of the top running backs -- the Carolina Panthers Christian McCaffrey and New York Giants Saquon Barkley -- left their respective game with injuries.
While McCaffrey's status is in flux, the Giants fear Barkley will be lost to a torn ACL.
Below is a look at the players who were injured in Week 2, their status and who the next player up will be if they are lost for any period of time.
Carolina Panthers
Christian McCaffrey, running back, ankle/lower leg
The NFL's highest-paid running back ($16 million a year) didn't return after limping off the field following a 7-yard touchdown run with just over 13 minutes remaining.