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Fansided · Sep 26, 2025

Saints expert reveals great secrets for Week 4 matchup vs. Bills

San Francisco 49ers v New Orleans Saints - NFL 2025 | Sean Gardner/GettyImagesThe Buffalo Bills are back at home for a Week 4 out-of-conference game where they will host the 0-3 New Orleans Saints in what should be a lopsided game in favor of the Bills. Buffalo comes into this game at 3-0 with wins over the Ravens, Jets, and Dolphins. While the offense is putting up 34 points per game, the defense is allowing about 24 points per game.

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