James Cook has been off to another great start in 2025. The Bills' running back is tied for the NFL league lead with four touchdowns in three games, and the next team he'll take on is the New Orleans Saints.
How will Cook fare in Week 4? Let's check out his previous Week 4 performances to see how he's done, per StatMuse.
Cook has struggled in three Week 4 games in his career. He's averaged 22.7 rushing yards and has scored just one touchdown total in Week 4. However, that's counting a 2022 Week 4 game when Cook, a rookie, did not get a single carried and was targeted just once.