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Buffalo Bills: Week 16 odds, lines and trends vs New England Patriots

Nov 1, 2020; Orchard Park, New York, USA; Buffalo Bills running back Zack Moss (20) falls into the end zone for a touchdown against the New England Patriots at Bills Stadium. Mandatory Credit: Rich Barnes-USA TODAY Sports

These are the odds, lines and trends for the Buffalo Bills entering Week 16.

The Buffalo Bills remain hot while stacking up dominant wins on their current four game winning streak. Last week’s easy victory over the Denver Broncos improved both their records against the spread (ATS) and cashing the over. Those records now stand at 9-5 and 10-4 respectively.