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Buffalo Bills guard Quinton Spain out with ankle injury

The Buffalo Bills lost another offensive lineman to injury, this time during Friday night’s preseason game against the Detroit Lions.

Quinton Spain, the presumed starter at left guard, is out for the game with an ankle injury. He was injured early in the second quarter during a running play. Another player rolled up on his leg from behind while he was opening a hole for Buffalo’s running back.

Spain is the latest casualty of the offseason and/or preseason along the offensive line. The Bills also have Mitch Morse (concussion), Ty Nsekhe (knee), and Russell Bodine (oblique) injured at the moment.