Southampton simply must beat south coast rivals Bournemouth if they are to improve their chances of survival.
Saints are currently four points adrift of safety after seven league games without a win.
But they have a great opportunity to pile the pressure on 17th-placed Swansea, who face an in-from Chelsea side this evening.
Bournemouth, on the other hand, are all but safe. However they've also struggled for form and are winless in their last four.
Who starts on the south coast? Confirmed line-ups below.
Southampton: McCarthy, Cedric, Yoshida, Hoedt, Bertrand, Tadic, Romeu, Lemina, Bednarek, Austin, Redmond.