Luton manager Rob Edwards says defender Reece Burke has a chance of returning from injury against Bournemouth.
A further 10 players remain unavailable for Saturday's game.
Bournemouth boss Andoni Iraola hopes to have Marcos Senesi back in the squad for the trip to Kenilworth Road.
Luis Sinisterra and Ryan Fredericks are still absent with respective hamstring and calf injuries, while Chris Mepham, Antoine Semenyo and Enes Unal have been unwell and will be monitored.
MATCH FACTS
Head-to-head
- Bournemouth won the reverse fixture 4-3, the fifth Premier League game won by a team trailing by three goals or more.