Brighton midfielder Pascal Gross is a fitness doubt after sustaining a muscle injury during Thursday's Europa League defeat by AEK Athens.
Lewis Dunk, James Milner and the recently ill Evan Ferguson will also be assessed, with head coach Roberto De Zerbi planning "a lot" of changes.
Bournemouth summer signings Tyler Adams and Alex Scott are continuing their recoveries from long-term injuries.
The Cherries have reported no fresh injury concerns.
- Brighton did the double over Bournemouth last season, winning 1-0 at home in February and 2-0 away in April.